SPECIFICATIONS :

  • First platform that correlates PK specific effects to PD endpoints
  • Kinetic binding studies using in-vivo  derived pharmacokinetic profiles
  • Direct or indirect measurement of target modulation (investigated in their native form)
  • Delivery of single or multiple drugs/biologics for schedule combination investigations or binding studies
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How It Works

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Specifications

  • LOW CELL COUNT

    Requires <100 cells per well

  • REAL-TIME TRACKING

    Time lapse fluorescence imaging performed throughout study

  • COMPLEX INFUSION PROFILES

    Program infusion profiles with <5 min step sizes

  • DELIVERY OF MULTIPLE DRUGS

    Each drug stream is controlled independently

  • IMMUNO- HISTOCHEMISTRY

    Perform established staining protocols on-chip

  • MOLECULAR ASSAYS

    Recover cultured cells for assaying off-chip
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NeoPKPD™
[In Development] Literature